吉林省长白山道地药材品质保障与新药资源开发重点实验室

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吉林省长白山道地药材重点实验室学生团队在全国大学生生命科学竞赛中荣获二等奖

|| 近日，第十一届全国大学生生命科学竞赛（创新创业类）吉林省赛区决赛结果正式揭晓。吉林省长白山道地药材品质保障与新药资源开发重点实验室（依托吉林医药学院）学生团队申报的项目“矢车菊素-3-O-葡萄糖苷干预HMGCR介导的胆固醇合成代谢改善过氧化氢诱导的细胞氧化应激”，经层层遴选，荣获国赛三等奖与省级二等奖。该项目由戴宇、孙斯雨、徐瑞雪、陈可阳、姜镕、朱丹六位同学共同完成。该项目围绕矢车菊素-3-O-葡萄糖苷（Cyanidin-...

吉林省长白山道地药材品质保障与新药资源开发重点实验室学生团队在第十一届全国大学生生命科学竞赛中斩获佳绩

|| 近日，第十一届全国大学生生命科学竞赛（科学探究类）吉林赛区决赛在吉林化工大学圆满落幕。本次竞赛吸引了全省28所高校的1112支队伍报名参与，经层层选拔，最终254支队伍晋级现场决赛，参赛规模与作品质量均创历届新高。吉林省长白山道地药材品质保障与新药资源开发重点实验室指导的学生代表队在此次竞赛中表现突出，荣获省级一等奖1项、二等奖1项，充分彰显了实验室在科研育人及创新人才培养方面的显著成效。全国大学生生命科学竞赛作为生命科学领域极具权威性与影响力的国家级赛事，...

福州大学专家团队来访吉林医药学院

|| 近日，福州大学专家团队来访吉林医药学院，围绕生物药光动力治疗技术国家地方联合工程研究中心（吉林分中心）成立一周年建设进展、吉林省长白山道地药材品质保障与新药资源开发重点实验室发展以及双方后续科研合作开展深入交流。福州大学黄明东教授、林忠辉教授、江龙光教授、李金羽教授、徐芃教授作为生物药光动力治疗技术国家地方联合工程研究中心主要成员参加交流。吉林医药学院科技处兼产业融合处处长冯宪敏及病原生物学研究中心骨干参加座谈。...

科研·进展

Licochalcone A in Folic Acid-targeted Nanoparticles for Precise Anticancer Effects in Breast Cancer.

AbstractBased on the high expression of folic acid (FA) receptors in triple-negative breast cancer cells, we encapsulated licochalcone A (LCA) in FA-modified polyethylene glycol-poly(lactic-co-glycolic) acid nanoparticles (NPs) for enhanced targeting and antitumor activity. In vitro experiments on 4T1 cells showed that NPs with FA modification exhibited excellent performance, including inhibition of ...

02/2026-07

Ac-HSP20 regulates autophagy and promotes the encystation of Acanthamoeba castellanii by inhibiting the PI3K/AKT/mTOR signaling pathway.

AbstractBackground: The encystation of Acanthamoeba castellanii has important ecological and medical significance. Blocking encystation is the key to preventing transmission and curing infections caused by A. castellanii. The formation of autophagosomes is one of the most important changes that occur during the encystation of Acanthamoeba. Our previous studies have shown that the heat shock protein ...

02/2026-07

pH responsive zwitterionic-to-cationic transition for safe self-defensive antibacterial application.

AbstractBacteria-induced infections have always been associated with various medical devices. The construction of an intelligent antimicrobial surface is an important challenge. In this study, we report the construction of a zwitterionic surface with good biocompatibility under physiological conditions and which shows an anti-adhesion effect on the original bacteria. Once the bacteria multiply, the ...

02/2026-07

Self-assembly and self-delivery of the pure nanodrug dihydroartemisinin for tumor therapy and mechanism analysis.

AbstractDihydroartemisinin (DHA), a plant-derived natural product, has recently been proven to be an effective therapeutic agent for cancer treatment. Nevertheless, the poor water solubility and low bioavailability of DHA seriously impede its clinical applications. Herein, a simple and green strategy based on the self-assembly of DHA was developed to synthesize carrier-free nanoparticles (NPs). The ...

02/2026-07